专利详情

专利名称	Use of 9, 10-anthraquinone compounds
申请号	US200913130130	专利类型	US
公开（公告）号	US8895725(B2)	公开（授权）日	2014.11.25
申请（专利权）人	中国科学院上海巴斯德研究所	发明（设计）人	Wang Shuguang;Zhong Jin;Kong Deyun;Hu Jue;Li Bo;Gao Wen;Gai Chunyan;Zhuang Changlong;Mao Haitao
主分类号	A61K31/192	IPC主分类号	A61K31/192;C09B1/473;A61K36/708;A61K36/74;A61K31/185;A61K31/704;A61K31/122;A61K31/7004;A61K36/482
专利有效期	Use of 9, 10-anthraquinone compounds 至Use of 9, 10-anthraquinone compounds	法律状态
说明书摘要	Use of 9,10-anthraquinone compounds of formula (I) or pharmaceutical salts thereof or plant extracts containing said compounds in the preparation of anti-HCV medicaments is disclosed, in which Y1 are Y2 are independently hydrogen, hydroxyl or groups of formula (II); and R1, R2, R3, R4, R5 and R6 are independently hydrogen, hydroxyl, carboxyl, cyano group, nitro group, groups of formula (III) or groups selected from those substituted or unsubstituted groups: amino, C1-C6 aliphatic hydrocarbon, C3-C7 cyclic aliphatic hydrocarbon, C1-C6 alkoxy, C2-C7 carbalkoxy, C1-C4 acyloxy, C6-C20 aryl, or 5 to 7 members heterocyclic or benzoheterocyclic thereof; or R5 and R6 form the group of formula (IV). The compounds of present invention are cheap, safe and effective because that they mostly come from traditional Chinese medicines and have better anti-HCV effects and lighter side effects.