专利详情

专利名称	Use of compounds extracted from Momordica charantia L. in the manufacture of medicaments for prevention and treatment of diabetes and obesity
申请号	US20090865843	专利类型	US
公开（公告）号	US8722634(B2)	公开（授权）日	2014.05.13
申请（专利权）人	中国科学院上海药物研究所	发明（设计）人	YE YANG;TAN MINJIA;KE CHANGQIANG;CHEN TONG;LI XIQIANG;KRAEGEN EDWARD;YE JIMING;JAMES DAVID;COONEY GREGORY
主分类号	A61K31/70	IPC主分类号	A61K31/70
专利有效期	Use of compounds extracted from Momordica charantia L. in the manufacture of medicaments for prevention and treatment of diabetes and obesity 至Use of compounds extracted from Momordica charantia L. in the manufacture of medicaments for prevention and treatment of diabetes and obesity	法律状态
说明书摘要	The present invention disclosed a medical use of cucurbitane triterpenoids represented by the following formula and isolated from Momordica charantia L. of Cucurbitaceae family in the preparation of medications for prevention and treatment of diabetes and obesity. The above cucurbitane triterpenoids may be acted as a glucose uptake stimulator, an agonist for the translocation of glucose transporter 4 (GLUT4) to the cell membrane, and an activator of adenosine monophosphate-activated protein kinase (AMPK). They may have potential for the prevention and treatment of diabetes and obesity.