2'',2-bisthiazole non-nucleoside compounds, preparation methods, pharmaceutical compositions and uses as hepatitis virus inhibitors thereof
- 申请号:US201113636488
- 专利类型:US
- 申请(专利权)人:中国科学院上海药物研究所
- 公开(公开)号:US8426606(B2)
- 公开(公开)日:2013.04.23
- 法律状态:
- 出售价格: 面议 立即咨询
专利详情
专利名称 | 2'',2-bisthiazole non-nucleoside compounds, preparation methods, pharmaceutical compositions and uses as hepatitis virus inhibitors thereof | ||
申请号 | US201113636488 | 专利类型 | US |
公开(公告)号 | US8426606(B2) | 公开(授权)日 | 2013.04.23 |
申请(专利权)人 | 中国科学院上海药物研究所 | 发明(设计)人 | NAN FAJUNZUO JIANPINGZHANG YANGMINGTANG WE |
主分类号 | C07D417/04 | IPC主分类号 | C07D417/04;A61K31/427 |
专利有效期 | 2'',2-bisthiazole non-nucleoside compounds, preparation methods, pharmaceutical compositions and uses as hepatitis virus inhibitors thereof 至2'',2-bisthiazole non-nucleoside compounds, preparation methods, pharmaceutical compositions and uses as hepatitis virus inhibitors thereof | 法律状态 | |
说明书摘要 | The present disclosure belongs to the field of pharmaceutical chemistry, and relates to a class of 2'',2-bisthiazole non-nucleoside compounds of following formula I, the preparation method and the pharmaceutical composition thereof. The compounds have both the anti-HBV and anti-HCV activities and are useful in treating hepatitides B and C. Pharmacokinetic tests showed the compounds have good bioavailability. |
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